(R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate

Name: (R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate
Brand: ChemScene
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CAS No. 719999-54-9
Cat. No. CS-W021147
Purity≥95%
MDL No.MFCD03839886

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate|CS-W021147

Structure of 719999-54-9

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General Information

CAS No. 719999-54-9
Cat. No. CS-W021147
Purity ≥95%
MDL No. MFCD03839886
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₂₀N₂O₂
Molecular Weight 200.28
Synonym(s) (r)-Tert-butyl pyrrolidin-2-ylmethylcarbamate
SMILES O=C(OC(C)(C)C)NC[C@@H]1NCCC1

Description

(R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate is a chiral building block featuring a stereodefined pyrrolidinylmethylamine scaffold. This bench-stable, moisture-tolerant reagent integrates seamlessly into peptide synthesis and medicinal chemistry workflows, enabling efficient access to bioactive amines through selective deprotection.

Application

(R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate serves as a chiral, bench-stable building block for asymmetric synthesis, enabling efficient access to enantiopure pyrrolidine-containing scaffolds. Its orthogonal protecting group compatibility facilitates sequential functionalization in complex molecule assembly. The carbamate moiety ensures excellent solubility and ease of purification, while the (R)-configured pyrrolidinomethyl unit provides a well-defined stereochemical handle for downstream applications in medicinal chemistry and catalyst development.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 50.36
LogP 1.2631
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

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(R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate

CAS No. 719999-54-9

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