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(S)-Pyrrolidin-2-ylmethanamine dihydrochloride

  • CAS No. 103382-84-9

  • Cat. No. CS-0043760
  • Purity≥95%
  • MDL No.MFCD11974898

*For research and further manufacturing use only, not for direct human use.

(S)-Pyrrolidin-2-ylmethanamine dihydrochloride|CS-0043760

Structure of 103382-84-9

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General Information

  • CAS No. 103382-84-9
  • Cat. No. CS-0043760
  • Purity ≥95%
  • MDL No. MFCD11974898
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₄Cl₂N₂
  • Molecular Weight 173.08
  • Synonym(s) 2-Pyrrolidinemethanamine, dihydrochloride, (S)-
  • SMILES NC[C@H]1NCCC1.[H]Cl.[H]Cl

Description

(S)-Pyrrolidin-2-ylmethanamine dihydrochloride is a chiral amine building block featuring a stereodefined pyrrolidine ring and primary amine functionality. This bench-stable, moisture-tolerant salt integrates readily into asymmetric synthesis workflows, serving as a pivotal scaffold for medicinal chemistry campaigns targeting CNS-active compounds and enzyme inhibitors.

Application

(S)-Pyrrolidin-2-ylmethanamine dihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the efficient construction of pyrrolidine-containing scaffolds. Its well-defined stereochemistry and dual amine functionality facilitate straightforward derivatization, including reductive amination and amide coupling. The dihydrochloride salt enhances solubility and stability for handling, supporting reliable performance in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.5407
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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