6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid

Name: 6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1404480-51-8
Cat. No. CS-0187196
Purity≥98%
MDL No.MFCD27635053

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid|CS-0187196

Structure of 1404480-51-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1404480-51-8
Cat. No. CS-0187196
Purity ≥98%
MDL No. MFCD27635053
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrN₃O₂
Molecular Weight 242.03
Synonym(s) 6-broMo-iMidazo[1,2-a]pyrazine-3-carboxylic acid
SMILES C1=C(C(=O)O)N2C=C(Br)N=CC2=N1

Description

6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid is a heterocyclic building block featuring a brominated imidazopyrazine core with a carboxylic acid handle. This scaffold enables direct functionalization in cross-coupling reactions and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds. The electron-deficient ring system enhances reactivity in palladium-catalyzed transformations.

Application

6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its bromine and carboxylic acid functionalities enable direct cross-coupling reactions and derivatization under standard conditions. The molecule exhibits good bench stability and facilitates efficient functional group manipulation, making it well-suited for medicinal chemistry campaigns requiring rapid analog synthesis and structural diversification.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 67.49
LogP 1.19
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

1404480-51-8 sigma1404480-51-8 manufacturer1404480-51-8 price1404480-51-8 structure1404480-51-8 SDSbuy 1404480-51-81404480-51-8 supplier1404480-51-8 uses1404480-51-8 molecular weightprice of 1404480-51-81404480-51-8 chemical name formula of 1404480-51-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid

CAS No. 1404480-51-8

Recommended Products