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Structure of 477535-41-4
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3-Bromo-5-(trifluoromethyl)benzaldehyde features a bromine atom and a trifluoromethyl group positioned meta to each other on the benzene ring, flanking an aldehyde functional group. This electronic configuration enhances reactivity in cross-coupling processes while maintaining stability under standard conditions. The molecule serves as a key building block for pharmaceutical intermediates and advanced materials.
3-Bromo-5-(trifluoromethyl)benzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling direct incorporation of bromo- and trifluoromethyl-functionalized aryl motifs. Its aldehyde group facilitates nucleophilic additions and condensation reactions, while the ortho-bromo substituent supports palladium-catalyzed cross-coupling transformations. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows involving Suzuki-Miyaura, Stille, or Buchwald-Hartwig couplings.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: