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CS-W001157 4
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3-(Boc-amino)-3-methyl-1-butanol

  • CAS No. 167216-22-0

  • Cat. No. CS-0162844
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Boc-amino)-3-methyl-1-butanol|CS-0162844

Structure of 167216-22-0

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General Information

  • CAS No. 167216-22-0
  • Cat. No. CS-0162844
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁NO₃
  • Molecular Weight 203.28
  • Synonym(s) tert-butyl (4-hydroxy-2-methylbutan-2-yl)carbamate
  • SMILES CC(C)(NC(OC(C)(C)C)=O)CCO

Description

This Boc-protected amino alcohol features a tertiary hydroxyl group flanked by a methyl substituent, enabling selective derivatization in peptide synthesis. The stable Boc moiety permits straightforward deprotection under mild acidic conditions, while the sterically hindered backbone resists racemization during coupling steps.

Application

3-(Boc-amino)-3-methyl-1-butanol serves as a versatile amino alcohol building block for peptide and heterocyclic synthesis. The Boc-protected amine enables orthogonal functional group manipulation, while the primary alcohol facilitates coupling reactions or derivatization. Its tertiary alcohol structure provides enhanced bench stability and simplifies purification. This compound functions effectively in standard amide coupling protocols and supports the construction of complex scaffolds in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.6721
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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