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Structure of 13916-98-8
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8-Fluoronaphthalen-2-ol features a fluorine atom at the 8-position of naphthalene, strategically positioned to modulate electronic properties and enhance metabolic stability. The phenolic hydroxyl group enables direct functionalization or hydrogen bonding interactions in synthetic applications. This bench-stable compound integrates readily into complex molecular architectures requiring precise spatial and electronic control.
8-Fluoronaphthalen-2-ol serves as a versatile building block for the synthesis of fluorinated heterocycles and bioactive molecules. Its ortho-hydroxyl group enables facile metal-catalyzed coupling reactions, while the 8-fluoro substituent provides enhanced electrophilicity for nucleophilic aromatic substitution. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating its use in iterative synthetic sequences for pharmaceutical and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: