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CS-W001157 4
Total: USD 88.00

3-(Bromomethyl)oxetane

  • CAS No. 1374014-30-8

  • Cat. No. CS-W018850
  • Purity≥95%
  • MDL No.MFCD20278240

*For research and further manufacturing use only, not for direct human use.

3-(Bromomethyl)oxetane|CS-W018850

Structure of 1374014-30-8

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General Information

  • CAS No. 1374014-30-8
  • Cat. No. CS-W018850
  • Purity ≥95%
  • MDL No. MFCD20278240
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BrO
  • Molecular Weight 151.00
  • Synonym(s) None
  • SMILES BrCC1COC1

Description

3-(Bromomethyl)oxetane is a highly reactive, bench-stable oxetane derivative featuring a bromomethyl group at the 3-position. This functionalized scaffold enables efficient coupling in synthetic transformations, particularly in C–C and C–heteroatom bond formation. The strained oxetane ring enhances reactivity while maintaining compatibility with diverse reaction conditions.

Application

3-(Bromomethyl)oxetane serves as a versatile electrophilic building block for C–C and C–heteroatom bond formation, enabling efficient incorporation of oxetane motifs into bioactive molecules. Its bromomethyl group undergoes smooth displacement with nucleophiles such as amines, thiols, and carbanions, while the oxetane ring provides enhanced metabolic stability and improved solubility in medicinal chemistry applications. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for modular synthesis workflows in drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.0277
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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