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CS-W001157 4
Total: USD 88.00

3-Bromooxetane

  • CAS No. 39267-79-3

  • Cat. No. CS-D1251
  • Purity≥98%
  • MDL No.MFCD08544402

*For research and further manufacturing use only, not for direct human use.

3-Bromooxetane|CS-D1251

Structure of 39267-79-3

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General Information

  • CAS No. 39267-79-3
  • Cat. No. CS-D1251
  • Purity ≥98%
  • MDL No. MFCD08544402
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅BrO
  • Molecular Weight 136.98
  • Synonym(s) Oxetane, 3-bromo-
  • SMILES BrC1COC1

Description

3-Bromooxetane is a strained, reactive three-membered cyclic ether bearing a bromine substituent at the 3-position. This configuration imparts high ring strain and facilitates regioselective ring-opening under mild conditions, enabling efficient incorporation into complex molecular architectures. The bromine moiety serves as a versatile handle for downstream functionalization via cross-coupling or nucleophilic substitution reactions.

Application

3-Bromooxetane serves as a versatile, bench-stable building block for the construction of oxetane-containing scaffolds in medicinal chemistry. Its strained three-membered ring enables efficient nucleophilic substitution and transition-metal-catalyzed coupling reactions, facilitating rapid access to bioactive molecules. The bromine atom provides a reliable handle for diversification via cross-coupling, enabling incorporation into complex pharmaceutical intermediates with high functional group tolerance and predictable reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P330-P370+P378-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   0.7801
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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