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Structure of 136411-21-7
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5-Bromo-4-(trifluoromethyl)thiazol-2-amine features a bromine atom at the 5-position and a strongly electron-withdrawing trifluoromethyl group at the 4-position, creating a uniquely reactive thiazole scaffold. This combination enables efficient cross-coupling and functionalization in medicinal chemistry and materials synthesis. The molecule exhibits bench-stable handling properties and compatibility with diverse reaction conditions.
5-Bromo-4-(trifluoromethyl)thiazol-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromine and electron-deficient thiazole core. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the amine functionality permits straightforward derivatization. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of functionalized heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: