2-Amino-5-bromo-4-methylthiazole

Name: 2-Amino-5-bromo-4-methylthiazole
Brand: ChemScene
Availability: InStock
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CAS No. 3034-57-9
Cat. No. CS-W005220
Purity≥97%
MDL No.MFCD09260911

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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2-Amino-5-bromo-4-methylthiazole|CS-W005220

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Description

2-Amino-5-bromo-4-methylthiazole is a heterocyclic building block featuring a brominated thiazole core with amino and methyl substituents. This configuration enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The compound exhibits robust stability under standard conditions, simplifying handling and integration into synthetic workflows.

Application

2-Amino-5-bromo-4-methylthiazole serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds prevalent in medicinal chemistry. Its amino and bromo functionalities support diverse coupling reactions, including palladium-catalyzed cross-couplings and nucleophilic substitutions, while the methyl group enhances stability and modulates electronic properties. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

General Information

CAS No. 3034-57-9
Cat. No. CS-W005220
Purity ≥97%
MDL No. MFCD09260911
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₅BrN₂S
Molecular Weight 193.06
Synonym(s) 5-bromo-4-methyl-thiazol-2-amine
SMILES CC1=C(Br)SC(N)=N1

Computational Chemistry Data

TPSA 38.91
LogP 1.79622
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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2-Amino-5-bromo-4-methylthiazole

CAS No. 3034-57-9

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