Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

  • CAS No. 1352796-65-6

  • Cat. No. CS-0145801
  • Purity≥97%
  • MDL No.MFCD13182191

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine|CS-0145801

Structure of 1352796-65-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1352796-65-6
  • Cat. No. CS-0145801
  • Purity ≥97%
  • MDL No. MFCD13182191
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄BFN₂O₂
  • Molecular Weight 224.04
  • Synonym(s) 2-FluoropyriMidine-5-boronic acid pinacol ester
  • SMILES CC1(C)C(C)(C)OB(C2=CN=C(F)N=C2)O1

Description

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine delivers a boronate handle ortho to a fluoropyrimidine core, enabling direct coupling in palladium-catalyzed cross-coupling reactions. The tetramethylboronate moiety enhances stability and reactivity under standard conditions, while the electron-deficient pyrimidine ring supports efficient functionalization. This compound serves as a key building block for medicinal chemistry and materials science applications.

Application

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The pyrimidine core provides a stable heterocyclic scaffold with defined regiochemistry, while the pinacol boronate group enables efficient coupling under mild conditions. Its bench stability and compatibility with diverse functional groups make it ideal for constructing complex molecular architectures in medicinal chemistry and materials science workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.24
  • LogP   0.9149
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1352796-65-6 sigma1352796-65-6 manufacturer1352796-65-6 price1352796-65-6 structure1352796-65-6 SDSbuy 1352796-65-61352796-65-6 supplier1352796-65-6 uses1352796-65-6 molecular weightprice of 1352796-65-61352796-65-6 chemical name formula of 1352796-65-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label