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CS-W001157 4
Total: USD 88.00

(9,9-Diphenyl-9H-fluoren-4-yl)boronic acid

  • CAS No. 1224976-40-2

  • Cat. No. CS-B1255
  • Purity≥98%
  • MDL No.MFCD29077672

*For research and further manufacturing use only, not for direct human use.

(9,9-Diphenyl-9H-fluoren-4-yl)boronic acid|CS-B1255

Structure of 1224976-40-2

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General Information

  • CAS No. 1224976-40-2
  • Cat. No. CS-B1255
  • Purity ≥98%
  • MDL No. MFCD29077672
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₁₉BO₂
  • Molecular Weight 362.23
  • Synonym(s) Boronic acid,B-(9,9-diphenyl-9H-fluoren-4-yl)-
  • SMILES OB(C1=CC=CC(C2(C3=CC=CC=C3)C4=CC=CC=C4)=C1C5=C2C=CC=C5)O

Description

This fluorenylboronic acid delivers a robust, electron-deficient boronate handle for Suzuki-Miyaura cross-coupling reactions. The sterically encumbered diphenylfluorene scaffold enhances stability and minimizes protodeboronation, enabling reliable functionalization under standard conditions.

Application

(9,9-Diphenyl-9H-fluoren-4-yl)boronic acid serves as a robust boronate building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its sterically hindered fluorene core enhances stability and facilitates purification, while the pendant phenyl groups provide excellent functional group tolerance. This reagent functions reliably in the construction of biaryl scaffolds and complex heterocycles relevant to pharmaceutical and materials chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   3.7295
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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