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Structure of 1351580-15-8
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(R)-1-(2,3-Difluorophenyl)ethanamine hydrochloride is a chiral amine featuring a sterically defined α-carbon and electron-withdrawing difluorophenyl group. This bench-stable salt facilitates enantioselective synthesis in medicinal chemistry, enabling efficient incorporation into bioactive scaffolds through straightforward coupling protocols under standard conditions.
(R)-1-(2,3-Difluorophenyl)ethanamine hydrochloride serves as a chiral building block for pharmaceutical intermediates, enabling stereoselective synthesis of bioactive molecules. Its bench-stable hydrochloride salt form facilitates handling and purification, while the ortho-difluoro substitution enhances metabolic stability and modulates electronic properties. The compound participates reliably in amide coupling, reductive amination, and transition-metal-catalyzed cross-coupling reactions, making it a versatile scaffold for medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: