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CS-W001157 4
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7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride

  • CAS No. 1350738-87-2

  • Cat. No. CS-W003911
  • Purity≥95%
  • MDL No.MFCD20278295

*For research and further manufacturing use only, not for direct human use.

7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride|CS-W003911

Structure of 1350738-87-2

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General Information

  • CAS No. 1350738-87-2
  • Cat. No. CS-W003911
  • Purity ≥95%
  • MDL No. MFCD20278295
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BrClNO
  • Molecular Weight 250.52
  • Synonym(s) 7-Bromo-3,4-dihydro-2H-benzo-[b][1,4]oxazine hydrochloride
  • SMILES BrC1=CC=C2C(OCCN2)=C1.Cl

Description

This hydrochloride salt features a brominated oxazine core with enhanced solubility and stability under standard conditions. The electron-deficient aromatic system facilitates electrophilic substitution, while the protonated nitrogen enables efficient coupling in synthetic sequences. A robust scaffold for medicinal chemistry and materials development.

Application

7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient access to pharmacologically relevant scaffolds. Its bromine functionality facilitates palladium-catalyzed cross-coupling reactions, while the oxazine core offers predictable reactivity in functional group interconversions. The hydrochloride salt enhances bench stability and solubility, simplifying purification and handling in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   2.6752
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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