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PEG2-NH-C2-NMe-Boc

  • CAS No. 1345680-97-8

  • Cat. No. CS-0214000
  • Molecule weight262.35
  • Purity≥95%
  • MDL No.MFCD32632559

*For research and further manufacturing use only, not for direct human use.

PEG2-NH-C2-NMe-Boc|CS-0214000

Structure of 1345680-97-8

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General Information

  • CAS No. 1345680-97-8
  • Cat. No. CS-0214000
  • Purity ≥95%
  • MDL No. MFCD32632559
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₆N₂O₄
  • Molecular Weight 262.35
  • Synonym(s) 2-[2-[[2-[Boc(methyl)amino]ethyl]amino]ethoxy]ethanol
  • SMILES O=C(OC(C)(C)C)N(CCNCCOCCO)C

Description

PEG2-NH-C2-NMe-Boc delivers a bifunctional handle combining a PEG2 spacer with a protected secondary amine, enabling site-specific conjugation in bioconjugation workflows. The NMe group enhances solubility and reduces nucleophilicity, while the Boc moiety provides stable protection under standard conditions.

Application

PEG2-NH-C2-NMe-Boc serves as a versatile bifunctional building block for peptide and macrocyclic synthesis, combining the solubility and stability of PEG2 with a protected secondary amine. The Boc group enables selective deprotection under mild acidic conditions, while the pendant amine facilitates conjugation via standard coupling reactions. Its well-defined structure supports reliable purification and functional group tolerance in complex synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   71.03
  • LogP   0.4518
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   8

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