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CS-W001157 4
Total: USD 88.00

Hydroxy-PEG2-acid

  • CAS No. 1334286-77-9

  • Cat. No. CS-0086325
  • Purity≥95%
  • MDL No.MFCD20646030

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG2-acid|CS-0086325

Structure of 1334286-77-9

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General Information

  • CAS No. 1334286-77-9
  • Cat. No. CS-0086325
  • Purity ≥95%
  • MDL No. MFCD20646030
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄O₅
  • Molecular Weight 178.18
  • Synonym(s) None
  • SMILES OC(CCOCCOCCO)=O

Description

Hydroxy-PEG2-acid is a bifunctional PEG-based reagent featuring a terminal hydroxyl group and a carboxylic acid moiety. This dual functionality enables site-specific conjugation in bioconjugation workflows, offering enhanced solubility and stability in aqueous environments. The short PEG spacer provides controlled spacing with minimal steric interference.

Application

Hydroxy-PEG2-acid serves as a versatile bifunctional linker for conjugation and solubilization in synthetic chemistry. Its hydroxyl group enables derivatization or coupling reactions, while the terminal carboxylic acid facilitates amide bond formation with amines under standard conditions. The PEG2 spacer provides enhanced solubility and reduced aggregation, making it ideal for applications in bioconjugation, peptide modification, and the construction of functionalized polymers.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.99
  • LogP   -0.5134
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   8

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