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Hydroxy-PEG2-(CH2)2-Boc

  • CAS No. 133803-81-3

  • Cat. No. CS-0058621
  • Purity≥97%
  • MDL No.MFCD20926380

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG2-(CH2)2-Boc|CS-0058621

Structure of 133803-81-3

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General Information

  • CAS No. 133803-81-3
  • Cat. No. CS-0058621
  • Purity ≥97%
  • MDL No. MFCD20926380
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂O₅
  • Molecular Weight 234.29
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCO

Description

Hydroxy-PEG2-(CH2)2-Boc features a hydroxyl-terminated PEG2 spacer flanked by a (CH2)2 linker and a Boc protecting group. This bifunctional intermediate enables site-specific conjugation in peptide synthesis and polymer chemistry, offering improved solubility and stability under standard conditions.

Application

Hydroxy-PEG2-(CH2)2-Boc serves as a versatile bifunctional building block for conjugation and protection strategies in synthetic chemistry. The terminal hydroxyl group enables derivatization via esterification or ether formation, while the Boc-protected amine facilitates selective coupling reactions. Its PEG2 spacer provides enhanced solubility and stability in aqueous environments, making it well-suited for applications in peptide modification, drug delivery systems, and the construction of functionalized scaffolds requiring orthogonal reactivity and facile purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.99
  • LogP   0.7437
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   8

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