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CS-W001157 4
Total: USD 88.00

Hydroxy-PEG8-Boc

  • CAS No. 1334177-84-2

  • Cat. No. CS-0110221
  • Purity≥98%
  • MDL No.MFCD11041105
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG8-Boc|CS-0110221

Structure of 1334177-84-2

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Description

Hydroxy-PEG8-Boc features a hydroxyl-terminated poly(ethylene glycol) chain of eight ethylene oxide units, protected at the terminal end with a tert-butoxycarbonyl group. This bifunctional architecture enables selective conjugation and controlled release in bioconjugation workflows. The PEG spacer provides enhanced solubility and reduced aggregation, while the Boc protection ensures stability during synthetic manipulations.

Application

Hydroxy-PEG8-Boc serves as a versatile, bench-stable building block for the synthesis of PEGylated compounds and bioconjugates. The Boc-protected hydroxyl group enables orthogonal handling in multistep syntheses, while the PEG8 spacer provides enhanced solubility and reduced aggregation. This reagent facilitates efficient coupling reactions under mild conditions and is compatible with diverse functional groups, making it ideal for constructing drug delivery systems and targeted therapeutics.

General Information

  • CAS No. 1334177-84-2
  • Cat. No. CS-0110221
  • Purity ≥98%
  • MDL No. MFCD11041105
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₄₆O₁₁
  • Molecular Weight 498.60
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCO

Computational Chemistry Data

  • TPSA   120.37
  • LogP   0.8433
  • H_Acceptors   11
  • H_Donors   1
  • Rotatable_Bonds   26

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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