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CS-W001157 4
Total: USD 88.00

Azido-PEG8-acid

  • CAS No. 1214319-92-2

  • Cat. No. CS-0114312
  • Purity≥98%
  • MDL No.MFCD21363300

*For research and further manufacturing use only, not for direct human use.

Azido-PEG8-acid|CS-0114312

Structure of 1214319-92-2

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General Information

  • CAS No. 1214319-92-2
  • Cat. No. CS-0114312
  • Purity ≥98%
  • MDL No. MFCD21363300
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₃₇N₃O₁₀
  • Molecular Weight 467.51
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Description

Azido-PEG8-acid features a terminal azide group and carboxylic acid functionality separated by an eight-ethylene glycol spacer. This bifunctional linker enables site-specific conjugation via click chemistry while providing aqueous solubility and reduced non-specific binding. Ideal for bioconjugation applications requiring stability and controlled presentation.

Application

Azido-PEG8-acid serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) due to its terminal azide group. The PEG8 spacer provides enhanced solubility and reduced non-specific binding, while the carboxylic acid functionality facilitates amide coupling with amines under standard activation conditions. This compound offers excellent bench stability, simplifies purification via precipitation or chromatography, and functions reliably in the synthesis of targeted conjugates and functionalized polymers.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   159.9
  • LogP   0.9042
  • H_Acceptors   10
  • H_Donors   1
  • Rotatable_Bonds   27

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