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Boc-NH-PEG3-propargyl

  • CAS No. 1333880-60-6

  • Cat. No. CS-0114917
  • Purity≥95%
  • MDL No.MFCD30534430

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG3-propargyl|CS-0114917

Structure of 1333880-60-6

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General Information

  • CAS No. 1333880-60-6
  • Cat. No. CS-0114917
  • Purity ≥95%
  • MDL No. MFCD30534430
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₅NO₅
  • Molecular Weight 287.35
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCNC(OC(C)(C)C)=O

Description

Boc-NH-PEG3-propargyl features a triethylene glycol spacer flanked by a Boc-protected amine and a terminal alkyne group. This bifunctional construct enables site-specific conjugation in bioorthogonal reactions while maintaining solubility and stability under standard conditions.

Application

Boc-NH-PEG3-propargyl serves as a versatile bifunctional building block for conjugation and polymer synthesis. The propargyl group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the Boc-protected amine offers orthogonal handling and stability. The PEG3 spacer provides enhanced solubility and reduced aggregation, making it ideal for bioconjugation, peptide modification, and the construction of functionalized materials in medicinal chemistry and diagnostic applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   66.02
  • LogP   1.1941
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   10

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