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CS-W001157 4
Total: USD 88.00

Propargyl-PEG2-NHBoc

  • CAS No. 869310-84-9

  • Cat. No. CS-0068579
  • Purity≥95%
  • MDL No.MFCD22418469

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG2-NHBoc|CS-0068579

Structure of 869310-84-9

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General Information

  • CAS No. 869310-84-9
  • Cat. No. CS-0068579
  • Purity ≥95%
  • MDL No. MFCD22418469
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₄
  • Molecular Weight 243.30
  • Synonym(s) None
  • SMILES O=C(NCCOCCOCC#C)OC(C)(C)C

Description

Propargyl-PEG2-NHBoc features a terminal alkyne for copper-catalyzed click chemistry, flanked by a short PEG spacer and a Boc-protected amine. This combination enables efficient conjugation while maintaining stability under standard conditions. The bifunctional design supports modular synthesis in bioconjugation and materials science applications.

Application

Propargyl-PEG2-NHBoc serves as a versatile bifunctional building block for conjugation and protection strategies in synthetic organic chemistry. The propargyl group enables reliable copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the Boc-protected amine offers orthogonal handling and stability. The PEG2 spacer enhances solubility and reduces aggregation, facilitating purification and downstream functionalization. This reagent is well-suited for peptide modification, bioconjugation, and modular synthesis of complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   56.79
  • LogP   1.1775
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   7

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