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CS-W001157 4
Total: USD 88.00

(6-Methyl-1H-indazol-5-yl)boronic acid

  • CAS No. 1310405-35-6

  • Cat. No. CS-0044925
  • Purity≥98%
  • MDL No.MFCD12028645

*For research and further manufacturing use only, not for direct human use.

(6-Methyl-1H-indazol-5-yl)boronic acid|CS-0044925

Structure of 1310405-35-6

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General Information

  • CAS No. 1310405-35-6
  • Cat. No. CS-0044925
  • Purity ≥98%
  • MDL No. MFCD12028645
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BN₂O₂
  • Molecular Weight 175.98
  • Synonym(s) 6-Methyl-1H-indazolyl-5-boronic acid
  • SMILES CC1=CC2=C(C=C1B(O)O)C=NN2

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions, delivering functionalized indazoles with high efficiency. The methyl group enhances solubility and stability under standard conditions, enabling reliable use in synthetic workflows.

Application

(6-Methyl-1H-indazol-5-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The boronic acid moiety exhibits excellent bench stability and tolerates a range of functional groups, facilitating straightforward purification and integration into complex molecular architectures. Its utility is well-established in medicinal chemistry for accessing indazole-based kinase inhibitors and other pharmacologically relevant frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   69.14
  • LogP   -0.44888
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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