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CS-W001157 4
Total: USD 88.00

Indazole-5-boronic acid

  • CAS No. 338454-14-1

  • Cat. No. CS-D0077
  • Purity≥97%
  • MDL No.MFCD06739151

*For research and further manufacturing use only, not for direct human use.

Indazole-5-boronic acid|CS-D0077

Structure of 338454-14-1

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General Information

  • CAS No. 338454-14-1
  • Cat. No. CS-D0077
  • Purity ≥97%
  • MDL No. MFCD06739151
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BN₂O₂
  • Molecular Weight 161.95
  • Synonym(s) 1H-Indazole-5-boronic acid
  • SMILES OB(O)C1=CC=C(NN=C2)C2=C1

Application

Indazole-5-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its stability, compatibility with diverse functional groups, and straightforward purification make it well-suited for medicinal chemistry campaigns and the synthesis of heterocyclic compounds.

Synthesis

  • Route1

    References

    • Basilea Pharmaceutica AG Patent: US6821980 B1, 2004 ; Location in patent: Page column 24 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   69.14
  • LogP   -0.7573
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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