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CS-W001157 4
Total: USD 88.00

5-Methyl-1H-indazol-4-yl-4-boronic acid

  • CAS No. 1245816-10-7

  • Cat. No. CS-W019606
  • Purity≥97%
  • MDL No.MFCD10001490

*For research and further manufacturing use only, not for direct human use.

5-Methyl-1H-indazol-4-yl-4-boronic acid|CS-W019606

Structure of 1245816-10-7

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General Information

  • CAS No. 1245816-10-7
  • Cat. No. CS-W019606
  • Purity ≥97%
  • MDL No. MFCD10001490
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BN₂O₂
  • Molecular Weight 175.98
  • Synonym(s) 5-Methyl-1H-indazole-4-boronic acid
  • SMILES OB(C1=C(C)C=CC2=C1C=NN2)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized indazoles with high efficiency. The methyl group enhances solubility and stability, while the electron-deficient core enables selective reactivity. Ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science.

Application

5-Methyl-1H-indazol-4-yl-4-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The boronic acid moiety exhibits good bench stability and functional group tolerance, facilitating straightforward purification and integration into complex molecular frameworks. Its utility is well-established in the synthesis of pharmaceutical intermediates and functionalized heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.14
  • LogP   -0.44888
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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