2-Bromo-5-iodopyridin-4-amine

Name: 2-Bromo-5-iodopyridin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 1300750-78-0
Cat. No. CS-0444329
Purity≥97%
MDL No.MFCD27959281

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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2-Bromo-5-iodopyridin-4-amine|CS-0444329

Structure of 1300750-78-0

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Description

2-Bromo-5-iodopyridin-4-amine delivers a dual halogenation pattern on a pyridine scaffold, enabling efficient cross-coupling strategies in medicinal chemistry. The bromo and iodo groups facilitate sequential Pd-catalyzed transformations, while the primary amine supports direct derivatization or conjugation. This bifunctional reactivity profile supports rapid diversification of heterocyclic architectures in target-oriented synthesis.

Application

2-Bromo-5-iodopyridin-4-amine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted pyridine scaffolds. Its dual halogen functionality supports sequential or orthogonal coupling reactions, facilitating the construction of complex heterocyclic systems. The amine group provides additional handle for derivatization, while the compound exhibits good bench stability and compatibility with standard Pd-catalyzed transformations.

General Information

CAS No. 1300750-78-0
Cat. No. CS-0444329
Purity ≥97%
MDL No. MFCD27959281
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄BrIN₂
Molecular Weight 298.91
Synonym(s) 4-amino-2-bromo-5-iodopyridine
SMILES C1=C(C(=CN=C1Br)I)N

Computational Chemistry Data

TPSA 38.91
LogP 2.0309
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromo-5-iodopyridin-4-amine

CAS No. 1300750-78-0

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