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CS-W001157 4
Total: USD 88.00

Dimethylmalonic acid

  • CAS No. 595-46-0

  • Cat. No. CS-W007894
  • Purity≥98%
  • MDL No.MFCD00004193

*For research and further manufacturing use only, not for direct human use.

Dimethylmalonic acid|CS-W007894

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General Information

  • CAS No. 595-46-0
  • Cat. No. CS-W007894
  • Purity ≥98%
  • MDL No. MFCD00004193
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₄
  • Molecular Weight 132.11
  • Synonym(s) Dimethylpropanedioic acid
  • SMILES O=C(O)C(C)(C)C(O)=O

Description

Dimethylmalonic acid features two methyl groups flanking a central carbon, creating a sterically hindered dicarboxylic acid with enhanced thermal stability. This structural motif enables reliable participation in decarboxylation reactions and serves as a key synthon in heterocyclic and pharmaceutical synthesis under standard bench conditions.

Application

Dimethylmalonic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted malonate derivatives and heterocyclic scaffolds. Its two methyl groups provide steric and electronic modulation, enhancing stability and directing regioselective transformations. The compound functions reliably in decarboxylation reactions and acts as a precursor in the synthesis of bioactive molecules and pharmaceutical intermediates, offering predictable reactivity and ease of purification under standard bench conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   0.1818
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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