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CS-W001157 4
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5-Bromo-3-methyl-2-pyridinecarbaldehyde

  • CAS No. 376587-53-0

  • Cat. No. CS-0039842
  • Purity≥97%
  • MDL No.MFCD07776420

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-methyl-2-pyridinecarbaldehyde|CS-0039842

Structure of 376587-53-0

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General Information

  • CAS No. 376587-53-0
  • Cat. No. CS-0039842
  • Purity ≥97%
  • MDL No. MFCD07776420
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO
  • Molecular Weight 200.03
  • Synonym(s) None
  • SMILES O=CC1=NC=C(Br)C=C1C

Description

5-Bromo-3-methyl-2-pyridinecarbaldehyde features a brominated pyridine core with a methyl group at the 3-position and an aldehyde function at the 2-position. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key building block for bioactive heterocycles and ligand synthesis under standard conditions.

Application

5-Bromo-3-methyl-2-pyridinecarbaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to functionalized pyridine scaffolds. Its bromo and aldehyde groups provide orthogonal handles for Suzuki-Miyaura coupling, nucleophilic addition, and condensation reactions, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and is compatible with standard purification techniques, facilitating its use in multi-step syntheses of bioactive molecules and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340-P405

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.96502
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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