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CS-W001157 4
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4-(1H-Pyrazol-3-yl)pyridine

  • CAS No. 17784-60-0

  • Cat. No. CS-0044140
  • Molecule weight145.17
  • Purity≥97%
  • MDL No.MFCD00115150

*For research and further manufacturing use only, not for direct human use.

4-(1H-Pyrazol-3-yl)pyridine|CS-0044140

Structure of 17784-60-0

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General Information

  • CAS No. 17784-60-0
  • Cat. No. CS-0044140
  • Purity ≥97%
  • MDL No. MFCD00115150
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃
  • Molecular Weight 145.17
  • Synonym(s) None
  • SMILES N=1C=CC(=CC1)C2=NNC=C2

Description

4-(1H-Pyrazol-3-yl)pyridine features a fused heteroaromatic system combining pyridine and pyrazole moieties, enabling strong coordination to metal centers. This structural motif enhances its utility in catalysis and ligand design, particularly in transition-metal-catalyzed coupling reactions. The molecule exhibits good stability under standard handling conditions and demonstrates favorable solubility in common organic solvents.

Application

4-(1H-Pyrazol-3-yl)pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of biologically active scaffolds through Pd-catalyzed cross-coupling reactions. Its dual nitrogen-rich framework offers enhanced solubility and hydrogen-bonding capacity, while maintaining bench stability and compatibility with common protecting group strategies.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.4717
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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