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CS-W001157 4
Total: USD 88.00

5-Bromo-2-carboxy-3-methylpyridine

  • CAS No. 886365-43-1

  • Cat. No. CS-W003404
  • Purity≥97%
  • MDL No.MFCD07375125

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-carboxy-3-methylpyridine|CS-W003404

Structure of 886365-43-1

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General Information

  • CAS No. 886365-43-1
  • Cat. No. CS-W003404
  • Purity ≥97%
  • MDL No. MFCD07375125
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₂
  • Molecular Weight 216.03
  • Synonym(s) 5-Bromo-3-methylpyridine-2-carboxylic acid
  • SMILES Brc1cnc(c(c1)C)C(=O)O

Description

N,N-Dimethylformamide di-n-propyl acetal, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Application

5-Bromo-2-carboxy-3-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions at the bromo position while retaining compatibility with the carboxylic acid and methyl groups. Its well-defined reactivity profile facilitates modular synthesis of substituted pyridine scaffolds relevant to pharmaceutical development. The compound exhibits good bench stability and is amenable to standard purification techniques.

Synthesis

  • Route1

    References

    • WO2008/100715 A1, ; Page/Page column 33-34 ; WO 2008/100715 A1
  • Route2

    References

    • US2013/96144 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.85072
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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