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CS-W001157 4
Total: USD 88.00

Propargyl-PEG2-bromide

  • CAS No. 1287660-82-5

  • Cat. No. CS-0147817
  • Purity≥95%
  • MDL No.MFCD24465329

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG2-bromide|CS-0147817

Structure of 1287660-82-5

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General Information

  • CAS No. 1287660-82-5
  • Cat. No. CS-0147817
  • Purity ≥95%
  • MDL No. MFCD24465329
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁BrO₂
  • Molecular Weight 207.07
  • Synonym(s) None
  • SMILES BrCCOCCOCC#C

Description

Propargyl-PEG2-bromide enables efficient copper-free click chemistry through its terminal alkyne and reactive bromide handle. This bifunctional reagent integrates seamlessly into bioconjugation workflows, offering rapid conjugation with azide-bearing molecules under physiological conditions. The short PEG spacer provides enhanced solubility and reduced steric hindrance, improving reaction kinetics and yield in complex biological environments.

Application

Propargyl-PEG2-bromide serves as a versatile bifunctional linker for bioconjugation and polymer synthesis. The terminal alkyne enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the bromide group facilitates nucleophilic substitution with amines or thiols. Its PEG2 spacer provides enhanced solubility and reduced aggregation, making it ideal for modular synthesis of functionalized biomolecules and responsive materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P301+P310-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362+P364-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.0477
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   6

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