Lot numbers can be found on the outside label of a product:
Bromo-PEG2-bromide
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CAS No. 31255-10-4
- Cat. No. CS-0109308
- Purity≥97%
- MDL No.MFCD00466590
*For research and further manufacturing use only, not for direct human use.
Structure of 31255-10-4
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General Information
- CAS No. 31255-10-4
- Cat. No. CS-0109308
- Purity ≥97%
- MDL No. MFCD00466590
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₁₂Br₂O₂
- Molecular Weight 275.97
- Synonym(s) None
- SMILES BrCCOCCOCCBr
Description
Bromo-PEG2-bromide is a bifunctional crosslinker featuring two reactive bromo groups flanking a short ethylene glycol chain. This structure enables efficient conjugation to nucleophilic sites on biomolecules or surfaces, facilitating the creation of stable linkages in bioconjugation workflows. The PEG spacer imparts solubility and reduces non-specific binding.
Application
Bromo-PEG2-bromide serves as a versatile bifunctional linker for the synthesis of polymer-conjugated molecules and functionalized surfaces. Its terminal bromide groups enable efficient coupling with nucleophilic substrates, including amines and thiols, under mild conditions. The short PEG2 spacer provides enhanced solubility and controlled spacing between functional moieties, facilitating applications in drug delivery systems and bioconjugation workflows.
Synthesis
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Route1
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In-stock
112-27-6 - ~90%
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In-stock
31255-10-4
References
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Li, Yi; Dong, Jianming; Xun, Zhiqing; Zeng, Yi; Yu, Tianjun; Han, Yongbin; Chen, Jinping; Li, Ying-Ying; Yang, Guoqiang Chemistry - A European Journal, 2013 , vol. 19, # 24 p. 7931 - 7936
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Route2
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507-16-4 -
In-stock
112-27-6
- ~58%
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In-stock
31255-10-4
References
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Farina, Paolo; Latter, Thomas; Levason, William; Reid, Gillian Dalton Transactions, 2013 , vol. 42, # 13 p. 4714 - 4724
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Route3
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In-stock
19249-03-7 - ~77%
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In-stock
31255-10-4
References
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Holmes, Brian T.; Snow, Arthur W. Patent: US2009/187037 A1, 2009 ; Location in patent: Page/Page column 2-3 ;
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 18.46
- LogP 1.8094
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 7
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Key Words
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