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Propargyl-PEG4-Br

  • CAS No. 1308299-09-3

  • Cat. No. CS-0109323
  • Purity≥95%
  • MDL No.MFCD28950764

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG4-Br|CS-0109323

Structure of 1308299-09-3

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General Information

  • CAS No. 1308299-09-3
  • Cat. No. CS-0109323
  • Purity ≥95%
  • MDL No. MFCD28950764
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉BrO₄
  • Molecular Weight 295.17
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCOCCBr

Description

Propargyl-PEG4-Br features a reactive propargyl bromide handle flanked by a four-ethylene glycol unit spacer, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). This bifunctional linker combines excellent solubility in aqueous and organic media with stable storage under standard conditions.

Application

Propargyl-PEG4-Br serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the reactivity of a terminal alkyne with a hydrolytically stable, water-soluble PEG4 spacer. The bromide functionality enables efficient nucleophilic substitution with amines, thiols, or azides, while the propargyl group supports copper-catalyzed azide-alkyne cycloaddition (CuAAC). Its stability under physiological conditions and ease of purification make it ideal for bioconjugation, probe labeling, and the construction of functionalized polymers and drug delivery systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.92
  • LogP   1.0809
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   12

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