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CS-W001157 4
Total: USD 88.00

Propargyl-PEG3-bromide

  • CAS No. 203740-63-0

  • Cat. No. CS-0114882
  • Purity≥97%
  • MDL No.MFCD28505517

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG3-bromide|CS-0114882

Structure of 203740-63-0

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General Information

  • CAS No. 203740-63-0
  • Cat. No. CS-0114882
  • Purity ≥97%
  • MDL No. MFCD28505517
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅BrO₃
  • Molecular Weight 251.12
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCBr

Description

Propargyl-PEG3-bromide features a terminal alkyne group flanked by a triethylene glycol spacer, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation. This water-soluble linker combines orthogonal reactivity with excellent stability under physiological conditions, facilitating site-specific labeling in complex biological systems.

Application

Propargyl-PEG3-bromide serves as a versatile bifunctional building block for bioconjugation and polymer synthesis. The terminal alkyne enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the primary bromide facilitates nucleophilic substitution reactions. Its PEG3 spacer provides enhanced solubility and reduced aggregation, making it ideal for labeling peptides, proteins, and functional materials with minimal steric interference.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   1.0643
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   9

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