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CS-W001157 4
Total: USD 88.00

3-Fluorocyclobutanamine hydrochloride

  • CAS No. 1284245-36-8

  • Cat. No. CS-0045538
  • Purity≥98%
  • MDL No.MFCD21642364

*For research and further manufacturing use only, not for direct human use.

3-Fluorocyclobutanamine hydrochloride|CS-0045538

Structure of 1284245-36-8

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General Information

  • CAS No. 1284245-36-8
  • Cat. No. CS-0045538
  • Purity ≥98%
  • MDL No. MFCD21642364
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClFN
  • Molecular Weight 125.57
  • Synonym(s) cis-3-Fluorocyclobutanamine hydrochloride
  • SMILES NC1CC(F)C1.[H]Cl

Description

3-Fluorocyclobutanamine hydrochloride offers a rigid, electron-deficient cyclobutane scaffold ideal for probing conformational constraints in bioactive molecule design. This bench-stable derivative integrates readily into medicinal chemistry campaigns requiring constrained amine motifs with enhanced metabolic resilience and improved membrane permeability.

Application

3-Fluorocyclobutanamine hydrochloride serves as a valuable building block for medicinal chemistry, enabling the incorporation of a strained cyclobutane scaffold with a fluorinated amine functionality. Its stability under standard handling conditions and compatibility with common coupling reactions facilitate efficient synthesis of bioactive molecules. The hydrochloride salt enhances solubility and simplifies purification, making it well-suited for use in peptide-like fragment libraries and targeted compound discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.8674
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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