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CS-W001157 4
Total: USD 88.00

4-(Dimethoxymethyl)piperidine

  • CAS No. 188646-83-5

  • Cat. No. CS-0214369
  • Purity≥95%
  • MDL No.MFCD09991908

*For research and further manufacturing use only, not for direct human use.

4-(Dimethoxymethyl)piperidine|CS-0214369

Structure of 188646-83-5

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General Information

  • CAS No. 188646-83-5
  • Cat. No. CS-0214369
  • Purity ≥95%
  • MDL No. MFCD09991908
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO₂
  • Molecular Weight 159.23
  • Synonym(s) 4-(dimethoxymethyl)piperidine Chemical
  • SMILES COC(C1CCNCC1)OC

Description

4-(Dimethoxymethyl)piperidine is a bench-stable, moisture-tolerant piperidine derivative featuring a dimethoxymethyl group at the C4 position. This functionalization enhances solubility in polar solvents and provides a versatile handle for downstream derivatization. The molecule integrates readily into medicinal chemistry campaigns targeting bioactive heterocycles.

Application

4-(Dimethoxymethyl)piperidine serves as a versatile building block in medicinal chemistry, enabling efficient access to diverse heterocyclic scaffolds. The dimethoxymethyl group functions as a masked aldehyde, undergoing acid-mediated cleavage to reveal a reactive aldehyde handle for reductive amination, imine formation, or further functionalization. Its stability under standard reaction conditions and compatibility with common protecting groups facilitate straightforward incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H315-H318-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   30.49
  • LogP   0.6049
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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