Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid

  • CAS No. 1268810-07-6

  • Cat. No. CS-M3251
  • Purity≥98%
  • MDL No.MFCD20660917

*For research and further manufacturing use only, not for direct human use.

1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid|CS-M3251

Structure of 1268810-07-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1268810-07-6
  • Cat. No. CS-M3251
  • Purity ≥98%
  • MDL No. MFCD20660917
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄O₂Si
  • Molecular Weight 182.29
  • Synonym(s) Cyclopropanecarboxylic acid, 1-[2-(trimethylsilyl)ethynyl]-
  • SMILES O=C(O)C1(C#C[Si](C)(C)C)CC1

Description

1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid features a sterically constrained cyclopropane ring bearing a silylated alkyne and carboxylic acid group, enabling direct incorporation into conjugation workflows. The trimethylsilyl moiety enhances stability and facilitates orthogonal deprotection, while the electron-deficient alkyne supports efficient copper-catalyzed coupling reactions under mild conditions.

Application

1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid serves as a versatile building block for the synthesis of cyclopropyl-containing alkynes, enabling efficient access to functionalized scaffolds via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The trimethylsilyl group provides enhanced stability and facilitates subsequent desilylation under mild conditions. Its carboxylic acid functionality allows for direct derivatization or incorporation into peptide-like architectures, making it valuable in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.732
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1268810-07-6 sigma1268810-07-6 manufacturer1268810-07-6 price1268810-07-6 structure1268810-07-6 SDSbuy 1268810-07-61268810-07-6 supplier1268810-07-6 uses1268810-07-6 molecular weightprice of 1268810-07-61268810-07-6 chemical name formula of 1268810-07-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label