Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

  • CAS No. 1071496-88-2

  • Cat. No. CS-0028733
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole|CS-0028733

Structure of 1071496-88-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1071496-88-2
  • Cat. No. CS-0028733
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁BN₂O₂
  • Molecular Weight 236.12
  • Synonym(s) None
  • SMILES CC1(C)C(C)(C)OB(C2=NN(C(C)C)C=C2)O1

Description

1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole features a boronate ester group that enables efficient Suzuki-Miyaura cross-coupling reactions. The tetramethyl-substituted dioxaborolane ring enhances stability and moisture tolerance, while the isopropylpyrazole scaffold provides steric bulk and electronic modulation. This reagent integrates readily into complex molecule synthesis under standard conditions.

Application

1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides orthogonal functionality and enhanced solubility, while the tetramethyl-dioxaborolane moiety enables efficient coupling with aryl and vinyl halides under mild conditions. Ideal for constructing biaryl and heteroaryl scaffolds in medicinal chemistry and materials science workflows.

Synthesis

  • Route1
    • null|null
      75-30-9
    • In-stock
      3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole|CS-W008230
      844501-71-9
    • ~%
    • In-stock
      1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole|CS-0028733
      1071496-88-2

    References

    • WO2008/122784 A1, ; Page/Page column 51-52 ; WO 2008/122784 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   36.28
  • LogP   1.7632
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1071496-88-2 sigma1071496-88-2 manufacturer1071496-88-2 price1071496-88-2 structure1071496-88-2 SDSbuy 1071496-88-21071496-88-2 supplier1071496-88-2 uses1071496-88-2 molecular weightprice of 1071496-88-21071496-88-2 chemical name formula of 1071496-88-2
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label