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Structure of 279226-70-9
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1-Methyl-1H-benzimidazole-5-carboxaldehyde features a benzimidazole core with a methyl group at the nitrogen and a formyl substituent at the 5-position, enabling direct integration into heterocyclic scaffolds. This electron-deficient aldehyde facilitates nucleophilic additions and condensation reactions under mild conditions, offering high reactivity and compatibility in synthetic transformations.
1-Methyl-1H-benzimidazole-5-carboxaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically active heterocycles. Its aldehyde functionality facilitates nucleophilic addition, reductive amination, and Ugi-type multicomponent reactions. The benzimidazole core provides metabolic stability and favorable pharmacophoric properties, while the methyl group enhances solubility and synthetic handle availability. This compound offers bench-stable, high-purity utility for scaffold diversification in API discovery workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: