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Structure of 1260758-33-5
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2,6-Dichloro-5-fluoronicotinaldehyde features a highly electron-deficient pyridine core with orthogonal halogen substituents enabling selective cross-coupling. This bench-stable aldehyde integrates readily into complex heterocycles and serves as a key building block for pharmaceutical intermediates requiring enhanced metabolic stability.
2,6-Dichloro-5-fluoronicotinaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds via condensation reactions. Its electron-deficient pyridine core enhances reactivity in nucleophilic additions and facilitates coupling with amines, hydrazines, and other nitrogen-containing nucleophiles. The ortho-chloro substituents provide synthetic handles for further functionalization, while the aldehyde group offers direct access to imines, oximes, and related derivatives. Bench-stable and amenable to purification by distillation or chromatography, it functions reliably in multi-step syntheses requiring precise functional group control.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: