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Structure of 1233513-13-7
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1-tert-Butoxycarbonyl-3-iodo-1H-pyrazole features a pyrazole core functionalized with a tert-butoxycarbonyl group at N1 and an iodine atom at C3, delivering a stable, electron-deficient heterocycle. This combination enables direct incorporation into cross-coupling reactions and facilitates rapid derivatization via palladium-catalyzed transformations. The protected nitrogen ensures compatibility with diverse reaction conditions while the iodide serves as a high-efficiency coupling handle.
1-tert-Butoxycarbonyl-3-iodo-1H-pyrazole serves as a versatile building block for the synthesis of functionalized pyrazole scaffolds, enabling efficient late-stage diversification via transition-metal-catalyzed cross-coupling reactions. The Boc group provides bench-stable protection of the pyrazole nitrogen, while the iodide facilitates reliable Suzuki, Stille, or Negishi coupling under standard conditions. Its compatibility with diverse functional groups and straightforward purification make it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: