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Structure of 92525-10-5
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3-Iodo-1-methyl-1H-pyrazole is a bench-stable, electron-deficient heterocycle featuring a reactive iodine substituent at the 3-position. This functional group enables efficient coupling in cross-coupling reactions, particularly in palladium-catalyzed transformations. The methyl group at the 1-position enhances solubility and modulates electronic properties, making this compound valuable for constructing complex nitrogen-containing scaffolds in medicinal chemistry and materials science.
3-Iodo-1-methyl-1H-pyrazole serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. The iodine substituent enables reliable Suzuki, Stille, and Negishi coupling reactions, facilitating the construction of biaryl and heteroaryl scaffolds. Its methyl group enhances stability and solubility, while the pyrazole core provides a rigid, polar scaffold compatible with diverse functional groups. This compound offers excellent bench stability, ease of handling, and straightforward purification—ideal for modular drug discovery and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: