tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate

Name: tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1227382-01-5
Cat. No. CS-W012209
Purity≥98%
MDL No.MFCD11976177

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate|CS-W012209

Structure of 1227382-01-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1227382-01-5
Cat. No. CS-W012209
Purity ≥98%
MDL No. MFCD11976177
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₀N₂O₆
Molecular Weight 288.30
Synonym(s) tert-Butyl 2,6-diazaspiro[3.3]-heptane-2-carboxylate oxalate
SMILES C(C(=O)O)(=O)O.C(=O)(OC(C)(C)C)N1CC2(C1)CNC2

Description

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate features a rigid spirocyclic core with two nitrogen atoms at the bridgehead positions, offering enhanced conformational control. The oxalate salt form improves solubility and stability, facilitating efficient incorporation into synthetic sequences under standard conditions. This scaffold serves as a valuable building block for complex heterocycles in medicinal chemistry.

Application

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate serves as a robust scaffold for spirocyclic diamine synthesis, enabling efficient access to constrained heterocyclic architectures. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate straightforward derivatization in medicinal chemistry workflows. The oxalate salt enhances solubility and crystallinity, simplifying purification and handling in preparative-scale applications.

Synthesis

Route1
- 1150618-17-9
- In-stock
  
  144-62-7
- ~%
- In-stock
  
  1227382-01-5
References
- MERCK FROSST CANADA LTD.; LACHANCE, Nicolas; LEGER, Serge; OBALLA, Renata, M.; POWELL, David; TRANMER, Geoffrey, K.; MARTINS, Evelyn; GAREAU, Yves Patent: WO2010/108268 A1, 2010 ; Location in patent: Page/Page column 69 ; WO 2010/108268 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 116.17
LogP -0.0177
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Azetidine compounds

Key Words

1227382-01-5 sigma1227382-01-5 manufacturer1227382-01-5 price1227382-01-5 structure1227382-01-5 SDSbuy 1227382-01-51227382-01-5 supplier1227382-01-5 uses1227382-01-5 molecular weightprice of 1227382-01-51227382-01-5 chemical name formula of 1227382-01-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate

CAS No. 1227382-01-5

Recommended Products