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CS-W001157 4
Total: USD 88.00

3-Methoxypropanoyl chloride

  • CAS No. 4244-59-1

  • Cat. No. CS-0695276
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methoxypropanoyl chloride|CS-0695276

Structure of 4244-59-1

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General Information

  • CAS No. 4244-59-1
  • Cat. No. CS-0695276
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClO₂
  • Molecular Weight 122.55
  • Synonym(s) None
  • SMILES COCCC(Cl)=O

Description

3-Methoxypropanoyl chloride is a reactive acylating agent featuring a methoxy-substituted propionyl moiety. This electrophilic reagent efficiently couples with alcohols and amines under mild conditions, enabling rapid synthesis of esters and amides. The electron-donating methoxy group enhances nucleophilic susceptibility while maintaining bench-stable handling characteristics.

Application

3-Methoxypropanoyl chloride serves as a versatile acylating agent for the efficient introduction of the 3-methoxypropanoyl group into organic substrates. It facilitates smooth amide and ester formation under mild conditions, exhibits good bench stability, and enables straightforward purification due to its low volatility and reactivity profile. Functions reliably in standard synthetic workflows involving nucleophiles such as amines, alcohols, and carboxylates.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H312-H314-H332
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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