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tert-Butyl n-[2-(ethylamino)ethyl]carbamate

  • CAS No. 113283-93-5

  • Cat. No. CS-0214890
  • Purity≥96%
  • MDL No.MFCD08729301

*For research and further manufacturing use only, not for direct human use.

tert-Butyl n-[2-(ethylamino)ethyl]carbamate|CS-0214890

Structure of 113283-93-5

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General Information

  • CAS No. 113283-93-5
  • Cat. No. CS-0214890
  • Purity ≥96%
  • MDL No. MFCD08729301
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₀N₂O₂
  • Molecular Weight 188.27
  • Synonym(s) tert-Butyl (2-(ethylamino)ethyl)carbamate
  • SMILES CCNCCNC(OC(C)(C)C)=O

Description

tert-Butyl n-[2-(ethylamino)ethyl]carbamate features a protected amine handle ideal for peptide synthesis and bioconjugation. The tert-butyl carbamate group enables orthogonal deprotection under mild acidic conditions, while the ethylaminoethyl side chain offers enhanced solubility and compatibility in aqueous systems. This combination delivers efficient coupling and stable intermediate formation in complex molecular architectures.

Application

tert-Butyl n-[2-(ethylamino)ethyl]carbamate serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient introduction of both amine and carbamate functionalities. Its tert-butyl carbamate group offers excellent stability under basic conditions and can be selectively removed under mild acidic conditions, facilitating deprotection without affecting other sensitive functional groups. The ethylaminoethyl side chain provides a reactive amine handle for conjugation or further derivatization, making it particularly useful in the synthesis of peptide analogs, macrocyclic compounds, and bioactive heterocycles.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.1206
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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