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Structure of 1213446-58-2
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This chiral amine features a difluoromethyl-substituted phenyl group attached to a stereodefined ethylamine scaffold. The para-difluoromethyl moiety imparts enhanced metabolic stability and modulates electronic properties, making it valuable for synthesizing bioactive molecules in medicinal chemistry.
(1S)-1-[4-(Difluoromethyl)phenyl]ethylamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated arylalkylamines with defined stereochemistry. Its difluoromethyl group imparts enhanced metabolic stability and modulated lipophilicity, while the secondary amine facilitates straightforward derivatization. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for use in multi-step synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: