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CS-W001157 4
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6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride

  • CAS No. 1191908-44-7

  • Cat. No. CS-0021526
  • Purity≥96%
  • MDL No.MFCD08544167

*For research and further manufacturing use only, not for direct human use.

6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride|CS-0021526

Structure of 1191908-44-7

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General Information

  • CAS No. 1191908-44-7
  • Cat. No. CS-0021526
  • Purity ≥96%
  • MDL No. MFCD08544167
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁ClFN
  • Molecular Weight 187.64
  • Synonym(s) None
  • SMILES NC1CCC2=C1C=C(F)C=C2.Cl

Description

6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride features a fluorinated indene core with a primary amine functionality, offering enhanced metabolic stability and improved membrane permeability. This bench-stable salt form facilitates handling in synthetic workflows, enabling efficient incorporation into pharmaceutical intermediates and bioactive molecule scaffolds.

Application

6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated indoline scaffolds. The amine functionality facilitates direct functionalization and coupling reactions, while the hydrochloride salt enhances stability and solubility for bench-scale synthesis. Its compatibility with standard amine protection and transformation protocols supports rapid diversification in API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.1935
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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