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*For research and further manufacturing use only, not for direct human use.
Structure of 1391354-92-9
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This chiral amine features a fluorinated indene core with a bench-stable hydrochloride salt, enabling straightforward handling and integration into asymmetric synthesis. The (1S) stereochemistry ensures high enantioselectivity in catalytic transformations, particularly in transition-metal-catalyzed C–H functionalizations and organocatalytic reactions.
(1S)-6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride serves as a chiral building block for asymmetric synthesis, offering high stereochemical integrity and bench stability. The fluorinated indene scaffold provides enhanced metabolic resistance and modulated lipophilicity, enabling its use in medicinal chemistry campaigns targeting CNS and oncology therapeutics. It functions effectively in amine coupling reactions, metal-catalyzed cross-couplings, and reductive amination protocols, with the hydrochloride salt ensuring ease of handling and purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: