6-Bromo-1,3,3-trimethylindolin-2-one

Name: 6-Bromo-1,3,3-trimethylindolin-2-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1190861-69-8
Cat. No. CS-0068948
Purity≥98%
MDL No.MFCD28133542

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-1,3,3-trimethylindolin-2-one|CS-0068948

Structure of 1190861-69-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Bromo-1,3,3-trimethylindolin-2-one features a brominated indolinone scaffold with enhanced stability and solubility in organic media. The electron-deficient aryl bromide enables efficient cross-coupling reactions, while the sterically shielded 3,3-dimethyl substitution prevents undesired side reactions. This compound serves as a key building block for synthesizing bioactive heterocycles under standard coupling conditions.

Application

6-Bromo-1,3,3-trimethylindolin-2-one serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position via palladium-catalyzed cross-coupling reactions. Its indolinone core provides inherent stability and compatibility with diverse reaction conditions, while the bromo group facilitates efficient derivatization. The trimethyl substitution enhances solubility and reduces aggregation during synthesis, supporting scalable access to complex heterocyclic scaffolds relevant to kinase inhibitor development.

General Information

CAS No. 1190861-69-8
Cat. No. CS-0068948
Purity ≥98%
MDL No. MFCD28133542
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₂BrNO
Molecular Weight 254.12
Synonym(s) 6-bromo-1,3,3-trimethylindol-2-one
SMILES O=C1N(C)C2=C(C=CC(Br)=C2)C1(C)C

Computational Chemistry Data

TPSA 20.31
LogP 2.7031
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indolin compounds

Key Words

6-Bromo-1,3,3-trimethylindolin-2-one sigma6-Bromo-1,3,3-trimethylindolin-2-one manufacturer6-Bromo-1,3,3-trimethylindolin-2-one price6-Bromo-1,3,3-trimethylindolin-2-one structure6-Bromo-1,3,3-trimethylindolin-2-one SDSbuy 6-Bromo-1,3,3-trimethylindolin-2-one6-Bromo-1,3,3-trimethylindolin-2-one supplier6-Bromo-1,3,3-trimethylindolin-2-one uses6-Bromo-1,3,3-trimethylindolin-2-one molecular weightprice of 6-Bromo-1,3,3-trimethylindolin-2-one6-Bromo-1,3,3-trimethylindolin-2-one chemical name formula of 6-Bromo-1,3,3-trimethylindolin-2-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Bromo-1,3,3-trimethylindolin-2-one

CAS No. 1190861-69-8

Recommended Products