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CS-W001157 4
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1-Isopropyl-1H-pyrazol-4-amine hydrochloride

  • CAS No. 1185293-23-5

  • Cat. No. CS-0459915
  • Purity≥98%
  • MDL No.MFCD11506624

*For research and further manufacturing use only, not for direct human use.

1-Isopropyl-1H-pyrazol-4-amine hydrochloride|CS-0459915

Structure of 1185293-23-5

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General Information

  • CAS No. 1185293-23-5
  • Cat. No. CS-0459915
  • Purity ≥98%
  • MDL No. MFCD11506624
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClN₃
  • Molecular Weight 161.63
  • Synonym(s) 1-Isopropyl-1H-pyrazol-4-ylamine hydrochloride
  • SMILES NC1=CN(C(C)C)N=C1.Cl

Description

1-Isopropyl-1H-pyrazol-4-amine hydrochloride features a pyrazole core functionalized with an isopropyl group at the 1-position and a primary amine at the 4-position, delivering enhanced solubility and stability under standard bench conditions. This salt form facilitates efficient incorporation into synthetic routes for bioactive heterocycles.

Application

1-Isopropyl-1H-pyrazol-4-amine hydrochloride serves as a versatile building block for pyrazole-based scaffolds in medicinal chemistry. Its amine functionality enables straightforward derivatization via amidation, alkylation, or coupling reactions. The hydrochloride salt enhances solubility and stability, facilitating handling and purification in standard synthetic workflows. Functions effectively in the construction of kinase inhibitors and other bioactive heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.468
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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