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CS-W001157 4
Total: USD 88.00

1-(4-Amino-3-ethoxyphenyl)piperidin-4-ol

  • CAS No. 1130146-98-3

  • Cat. No. CS-M1148
  • Purity≥97%
  • MDL No.MFCD19514095

*For research and further manufacturing use only, not for direct human use.

1-(4-Amino-3-ethoxyphenyl)piperidin-4-ol|CS-M1148

Structure of 1130146-98-3

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General Information

  • CAS No. 1130146-98-3
  • Cat. No. CS-M1148
  • Purity ≥97%
  • MDL No. MFCD19514095
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₀N₂O₂
  • Molecular Weight 236.31
  • Synonym(s) 1-(4-Amino-3-ethoxyphenyl)-4-piperidinol
  • SMILES NC1=CC=C(C=C1OCC)N2CCC(O)CC2

Description

This piperidinol derivative features a 4-amino-3-ethoxyphenyl group linked to a hydroxylated piperidine scaffold, delivering a bench-stable, moisture-tolerant core for medicinal chemistry applications. The electron-rich aromatic moiety integrates readily into bioactive scaffolds, while the pendant hydroxyl enables strategic derivatization.

Application

1-(4-Amino-3-ethoxyphenyl)piperidin-4-ol serves as a versatile building block for medicinal chemistry campaigns, enabling the construction of bioactive heterocycles through standard amide coupling and reductive amination protocols. The molecule combines a phenolic piperidinol core with an ethoxy-substituted aniline moiety, offering enhanced solubility and functional group tolerance. Its bench-stable nature facilitates straightforward purification and integration into multi-step syntheses of kinase inhibitors and CNS-targeted compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.72
  • LogP   1.6286
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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